Acta Scientific Nutritional Health

Research ArticleVolume 1 Issue 2

Changing Trend in Diabetes Mellitus

Avinash Shankar1*, Abhishek Shankar2, Shubham3, Amresh Shankar4 and Anuradha Shankar5

1Post Graduate in Endocrinology and Metabolism (AIIMS), RA Hospital and Research Centre, Warisaliganj (Nawada) Bihar, India
2All India Institute of Medical Sciences, New Delhi, India
3Max Hospital, Delhi, India
4Medical Officer, State Medical Services, Government of Bihar, Patna, India
5Medical Officer, RBSK, Government of Jharkhand, Ranchi, India

*Corresponding Author: Avinash Shankar, Post Graduate in Endocrinology and Metabolism (AIIMS), RA Hospital and Research Centre, Warisaliganj (Nawada) Bihar, India.

Received: June 09, 2017; Published: June 24, 2017

Citation: Avinash Shankar., et al.. “Changing Trend in Diabetes Mellitus”. Acta Scientific Nutritional Health 1.2 (2018).

Abstract

  Diabetes mellitus, progressively increasing worldwide but India is considered Diabetes capital of the world with a projected incidence of 109 million by 2035, as this disease of luxury is affecting even down trodden daily wage earner and hard workers both sexes equally due to emergence of toxic non-nutrients in the diet, drinks and oil solely caused by rampant use of fertilizer, chemicals, pesticides, hormones, preservatives and processing.

  In addition, patients show increased tolerability to high blood sugar level and create suspicion regarding etiopathogenetic of hyperglycaemia while altered hepatic profile and better glycemic control on adjunction of hepatologic with antidiabetic drug with restricted first diet to 100 calories suggest hyperglycaemia as a combined effect of hepatic and pancreatic dysfunction. In present study 20,000 population of 20 Dalit hamlets and 10 villages of Nawada district aged > 35 yrs screened for blood sugar, clinical examination and patients of Diabetes mellitus attending DRC of RA Hospital and research Centre, Warisaliganj (Nawada) evaluation revealsAdjuvant hepatologic with antidiabetic drug and dietary restriction check circadian variation of blood sugar and ensure blood sugar bioregulation with continued tapering of anti-diabetic dose without any consequent sequel or adversity. Toxic non-nutrient dietary constituents suppress secretion and production of GLP 1 in the L cells of mucosal lining of the small intestine and stimulate production of Dipeptidyl peptidase 4 which further increases GPL 1 degradation resulting in decrease in volume of insulin secreting B cells in the pancreas and decline in insulin release manifesting as hyperglycaemia.

Keywords: Glycemic Control; Bioregulation; Circadian Variation; Dysfunction

Copyright: © 2018 Avinash Shankar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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