Hoori Shehwar1*, Shaukat Ali2 and Saera Suhail Kidwai3
1Consultant Neurologist, Neuro Clinic and Falij Care (NCFC), Karachi, Pakistan
2Professor, Neuro Spinal Medical and Cancer Care Institute, Karachi, Pakistan
3Professor, Department of Medicine, Fazaiya Ruth Pfau Medical College, Pakistan
*Corresponding Author: Hoori Shehwar, Consultant Neurologist, Neuro Clinic and Falij Care (NCFC), Karachi, Pakistan.
Received: December 30, 2019; Published: January 20, 2020
Multiple sclerosis (MS) can be widely identified as a neurological disability which affects a wider population of young adults. in the UK. One of the major areas of treatment and control of the disease is in the area of symptom control. Although conventional drug-based interventions show some efficacy in alleviating symptoms; the benefits are marginal and often leads to long term adverse effects. On the other hand, there is a tremendous prospect of cannabis-based interventions which has been under extensive research and experimentation since centuries. In the recent past, the effects of non-psychoactive components of cannabis such as cannabinoids have been shown through animal samples as well as randomised controlled trials to have some efficacy in pain reduction and alleviating symptoms of muscular spasticity.
Based on a systematic review methodology, online databases are searched in this review for identifying and selecting recent research using established inclusion criteria and exclusion criteria. The purpose of this paper to develop a review of the efficacy of cannabinoids in the treatment and control of MS.
Findings indicate that the efficacy of cannabinoids and cannabis-based interventions in the treatment and control of MS was repeatedly highlighted in alleviating symptoms of pain and spasticity. In selected research findings, anti-inflammatory and anti-apoptotic properties of the compound were detected showing potential for addressing neuro-degeneration in MS. However, a wide range of other potential effects such as cognitive repair, mobility and treatment of other symptoms were found to be questionable due to the lack of clinical evidence.
Keywords: Cannabinoid; Multiple Sclerosis; Pain; Spasticity; Neurodegenartion; Side Effects
Citation: Hoori Shehwar., et al. “Use of Cannabinoid is Effective in Multiple Sclerosis Symptoms".Acta Scientific Neurology 3.2 (2020): 01-05.
Copyright: © 2020 Hoori Shehwar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.