Acta Scientific Microbiology (ASMI) (ISSN: 2581-3226)

Short Commutation Volume 3 Issue 1

Triage for Severe Dengue Using Early Severe Dengue Identifier

Ashok Rattan1* and Mohit Agrawal2

1Pathkind Labs, Gurgaon, Haryana, Jaipur, India

2Associate Professor, Department of Microbiology, Mahatma Gandhi Medical College, Jaipur, India

*Corresponding Author: Ashok Rattan, Pathkind Labs, Gurgaon, Haryana, Jaipur, India.

Received: November 06, 2019; Published: December 04, 2019

×

  Dengue is a mosquito transmitted viral infection. It is the leading arthropod-borne viral disease in the world. Since 1950 the number of people infected has risen steadily and it has become a health threat with an estimated 3.6 billion persons at risk [1]. In distribution also it has become a global problem. While Southeast Asia and India were well known areas of endemicity now South and Central America have also become endemic. Even developed countries like USA where it was considered under control, is also facing the threat of dengue [2]. Dengue which was once considered a pediatric illness is now increasingly being reported in adults as well. This geographic and demographic expansion warrants more studies on dengue infections.

  Dengue viruses (DENV) are members of the family Flaviviridae, genus Flavivirus. They are small, enveloped viruses having a single positive strand of ribonucleic acid (RNA) [3]. There are four serotypes of dengue based on neutralization tests, DENV-1, DENV-2, DENV-3, and DENV-4. Though the serotypes show extensive cross-reactivity, they are distinguishable with the highly specific plaque reduction neutralization test (PRNT) [4]. Human and several sub-human primates are vertebrate hosts of the virus. Virus is transmitted to them by Aedes group of mosquitoes like A. aegypti, A. albopictus and A. polynesiensis.

×

References

  1. World Health organization. Dengue and severe dengue (2019).
  2. Morens DM and Fauci AS. “Dengue and hemorrhagic fever: a potential threat to public health in the United States”. Journal of the American Medical Association 299 (2008): 214-216.
  3. Chambers TJ., et al. “Flavivirus genome organization, expression, and replication”. Annual Review of Microbiology 44 (1990): 649-688.
  4. Thomas SJ., et al. “Dengue plaque reduction neutralization test (PRNT) in primary and secondary dengue virus infections: How alterations in assay conditions impact performance”. American Society of Tropical Medicine and Hygiene 5 (2009): 825-833.
  5. Rigau-Pérez JG., et al. “Dengue and dengue haemorrhagic fever”. Lancet 352 (1998): 971-977.
  6. Srikiatkhachorn A., et al. “Natural history of plasma leakage in dengue hemorrhagic fever: a serial ultrasonic study”. Pediatric Infectious Disease Journal4 (2007): 283-290.
  7. Nimmannitya S., et al. “Dengue and chikungunya virus infection in man in Thailand, 1962-64. Observations on hospitalized patients with haemorrhagic fever”. American Journal of Tropical Medicine and Hygiene6 (1969): 954-971.
  8. Dengue haemorrhagic fever: diagnosis, treatment, prevention and control, 2nd ed. Geneva, World Health Organization (1997).
  9. Dengue: guidelines for diagnosis, treatment, prevention and control. Geneva, World Health Organization (2009).
  10. Flipse J., et al. “Antibody-Dependent Enhancement of Dengue Virus Infection in Primary Human Macrophages; Balancing Higher Fusion against Antiviral Responses”. Scientific Reports 6 (2016): 29201.
  11. Nguyen MT., et al. “An Evidence-Based Algorithm for Early Prognosis of Severe Dengue in the Outpatient Setting”. Clinical Infectious Diseases 5 (2017): 656-663.
  12. Ranjit S and Kissoon N. “Dengue hemorrhagic fever and shock syndromes”. Pediatric Critical Care Medicine 12 (2011): 90-100.
  13. Vu HH., et al. “Regional differences in the growing incidence of dengue Fever in Vietnam explained by weather variability”. Tropical Medicine and Health 1 (2014): 25-33.
×

Citation

Citation: Ashok Rattan and Mohit Agrawal. "Triage for Severe Dengue Using Early Severe Dengue Identifier".Acta Scientific Microbiology 3.1 (2020): 26-29.



Member In






News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for March Issue
    The last date for submission of articles for regular Issues is March 15, 2020.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US