Acta Scientific Microbiology

Review ArticleVolume 1 Issue 9

Helicobacter pylori: Is there an Association with Oral Pathologies? A Traditional Review

Luca Vigano1*, Casu Cinzia2, Andrea Oliveira3 and Pierluigi Guerrieri4

1Department of Radiology, San Paolo Dental Building, University of Milan, Italy
2Private Dental Practice, Cagliari, Italy
3San Paolo Dental Building, University of Milan Italy
4IRCCS Ca Granda Fondation General Hospital University of Milan Italy

*Corresponding Author: Luca Viganò, Department of Radiology, San Paolo Dental Building, University of Milan, Italy.

Received: July 30, 2018; Published: August 22, 2018

Citation: Luca Vigano., et al.Helicobacter pylori: Is there an Association with Oral Pathologies? A Traditional Review”. Acta Scientific Microbiology 1.9 (2018).


Background: Given the works of Marshall and Warren, Helicobacter pylori found its place in scientific literature. Once evaluated the correlation between the microorganism and gastric pathologies, next studies are researching a possible role of H. pylori in the oral pathologies, since there is a direct continuity between oral cavity and stomach. Indeed, nowadays, it’s possible to affirm that oral cavity represents the main extra-gastric reservoir of H. pylori.

Objectives: The purpose of this study is to analyze the relationship between H. pylori and important pathologies in the field of oral medicine.

Materials and Methods: This review takes in exam the articles published on PubMed in which the link between H. pylori and oral pathologies is analyzed. The pathologies appraised are: periodontitis, caries, neoplastic pathology, recurrent aphthous stomatitis, oral lichen planus, leukoplakia, peri-implantitis. Where possible, meta-analysis extracted from PubMed were considered.

Results: H. pylori is detectable in high numbers in mouth when dental plaque and poor oral hygiene conditions are present. This topographic association is related firstly to a higher risk of re-infection and, secondly, it can imply a causal connection which could assume a remarkable plausibility within the infectious oral pathologies.

Conclusions: Current data show a possible correlation between H. pylori infection and periodontitis, caries, recurrent aphthous stomatitis, oral lichen planus and leukoplakia. It seems, however, there is no positive correlation between oral squamous cell carcinoma and the microorganism. Regarding peri-implantitis, the bacterial strain-typing only demonstrates the presence of H. pylori in periimplantitis sites without studying a potential causal link..

Keywords: Helicobacter pylori; Oral Pathologies

Copyright: © 2018 Luca Vigano., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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