Acta Scientific Microbiology

Research ArticleVolume 1 Issue 9

Emergence of Multi Drug Resistant Microorganisms from Various Sterile Body Fluids in a Teaching Hospital of a Developing Country

Bhawna Sharma1 and Dimple Kasana2*

1Assistant Professor, VMMC and Safdarjung Hospital, New Delhi, India
2Professor and Consultant, VMMC and Safdarjung Hospital, New Delhi, India

*Corresponding Author: Dimple Kasana, Professor and Consultant, VMMC and Safdarjung Hospital, New Delhi, India.

Received: July 06, 2018; Published: August 07, 2018

Citation: Bhawna Sharma and Dimple Kasana. “Emergence of Multi Drug Resistant Microorganisms from Various Sterile Body Fluids in a Teaching Hospital of a Developing Country”. Acta Scientific Microbiology 1.9 (2018).


  Sterile body sites, if infected by micro-organisms can lead to severe morbidity and mortality. Infections caused by multidrug resistant (MDR) bacteria remain a public health threat. Hence, early diagnosis and prompt initiation of empiric treatment is necessary. Thus, this present study was undertaken to evaluate the prevalence of Multi drug resistant (MDR) organisms in different sterile body fluid. This study was done on a retrospective basis for a period of one year from January 2017 to February 2018 in Department of Microbiology of a tertiary care hospital, New Delhi. A total of 2000 sterile body fluid samples were analyzed and all were processes within 2 hours of collection. Out of which 20% (400/2000) were shown bacterial growth and 85% were sterile after 48 hours of incubation. Out of 400 samples in our study, most commonly received fluid is as Pleural (46.60%). In our study, the predominant Gram negative organisms were E. coli (87), Klebsiella spp. (65), Pseudomonas spp. (41), Acinetobacter spp. (34), Citrobacter spp. (26) and in Gram positive S. aureus (34), α Streptococcus (28), Enterococcus spp. (23), Pneumococcus pneumoniae (18) and CONS (16). Among Staphylococcus aureus 59% were MRSA. E. coli isolates showed highest resistance to Fluoroquinolones, Cephalosporins, and moderate resistance to beta-lactam beta-lactamase inhibitors. This high MDR level may be due to inappropriate use of commonly prescribed antibiotics

Keywords: Sterile Body Fluid; Multi Drug Resistant; Gram Negative; Gram Positive

Copyright: © 2018 Bhawna Sharma and Dimple Kasana. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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