Acta Scientific Microbiology

Research ArticleVolume 1 Issue 8

Phylogenetic Study and Principal Component Analysis of the Matrix Gene of the Influenza A Virus Subtype H1N1 from 1918 - 1999

Raul Isea

Fundacion Instituto de Estudios Avanzados, Hoyo de la Puerta, Baruta, Venezuela

*Corresponding Author: Raul Isea, Fundacion Instituto de Estudios Avanzados, Hoyo de la Puerta, Baruta, Venezuela.

Received: June 26, 2018; Published: July 13, 2018

Citation: Raul Isea. “Phylogenetic Study and Principal Component Analysis of the Matrix Gene of the Influenza A Virus Subtype H1N1 from 1918 - 1999”. Acta Scientific Microbiology 1.8 (2018).

Abstract

   The goal of this work is to review the evolution of the 81 matrix genes of influenza A Virus subtype H1N1 from 1918 until 1999 with phylogenetic tools and compare the results with the principal component analysis (PCA). The results obtained from the phylogenetic analysis are consistent with the evolution of the virus according to the scientific literature while the results of the PCA reveals that the sequences can be grouped in 7 clusters where the strain that was isolated in Tientsin, China in 1977, is not included in these clusters.

Keywords: : Influenza; H1N1; Phylogenetic; Matrix Gene; Principal Component Analysis; PCA

Copyright: © 2018 Raul Isea. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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