Department of Hygiene and Environmental Protection, Ministry of Public Health, Tunis, Tunisia
*Corresponding Author: Ahmed Tabbabi, Department of Hygiene and Environmental Protection, Ministry of Public Health, Tunis,Tunisia.
Received: June 25, 2018; Published: July 06, 2018
Citation: Ahmed Tabbabi. "The Potential Role of Exosomes in the Pathogenesis of Infectious Diseases and their Importance for Treatment and Prevention”. Acta Scientific Microbiology 1.8 (2018).
iThe field of exosome research is expanding, with a dramatic increase in publications in recent years. These small vesicles (30 - 100 nm) of endocytic origin were first proposed to function as a means for reticulocytes to eradicate the transferrin receptor then maturation in erythrocytes  and were later named exosomes. Exosomes are formed by inward budding of endosomes, production of multivesicular bodies and are released into the environment by fusion of multivesicular bodies with plasma membrane . Since the first discovery of exosomes, a large range of cells has been shown to release these vesicles. Exosomes have also been detected in several biological fluids, including plasma, nasal wash fluid, saliva and [3-5] breast milk. Moreover, it has been shown that the content and function of exosomes depends on the cell of origin and the conditions under which they are produced. A variety of functions have been demons concentrated for exosomes, such as induction of tolerance against allergen , eradication of established tumors in mice  inhibition and activation of natural killer cells , promotion of differentiation in T  regulatory cells, stimulation of T  cell proliferation and induction of T cell apoptosis. It is important to note that the majority of studies using exosomes purified in vitro or from various biological fluids  and not in vivo.
Copyright: © 2018 Ahmed Tabbabi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.