Acta Scientific Microbiology

EditorialVolume 1 Issue 4

Bacterial Membrane Vesicles: New Therapeutic Prospectives

Cinzia Giagulli*

Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy

*Corresponding Author: Cinzia Giagulli, Section of Microbiology, Department of Molecular and Translational Medicine, School of Medicine, University of Brescia, Brescia, Italy.

Received: February 19, 2018; Published: March 01, 2018

DOI: 10.31080/ASMI.2018.01.0030

Citation: Cinzia Giagulli. “Bacterial Membrane Vesicles: New Therapeutic Prospectives”. Acta Scientific Microbiology 1.4 (2018).

Bibliography

  1. Jung AL., et al . “Legionella pneumophila Outer Membrane Vesicles: Isolation and Analysis of Their Pro-inflammatory Potential on Macrophages”. Journal of Visualized Experi - ments (2017): 120.
  2. Nicholas A., et al . “Clostridium difficile-derived membrane vesicles induce the expression of pro-inflammatory cyto - kine genes and cytotoxicity in colonic epithelial cells in vi- tro”. Microbial Pathogenesis 107 (2017): 6-11.
  3. Ho MH., et al . “Characterization of Innate Immune Respons - es of Human Endothelial Cells Induced by Porphyromo - nas gingivalis and Their Derived Outer Membrane Vesicles”. Frontiers in Cellular and Infection Microbiology 6 (2016): 139.
  4. Zariri A., et al . “Meningococcal Outer Membrane Vesicle Composition-Dependent Activation of the Innate Immune Response”. Infection and Immunity 84.10 (2016): 3024- 3033.
  5. Jeon H., et al . “Variation among Staphylococcus aureus membrane vesicle proteomes affects cytotoxicity of host cells”. Microbial Pathogenesis 93 (2016): 185-193.
  6. Luan L., et al . “Comparative Transcriptome Profiles of Hu - man Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A”. Scientific Reports 7 (2017): 40050.
  7. Malgorzata-Miller G., et al . “Bartonella quintana lipopoly - saccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications”. Sci - entific Reports 6 (2016): 34221.
  8. Chatterjee D., et al . “Vibrio cholerae O395 outer membrane vesicles modulate intestinal epithelial cells in a NOD1 pro- tein-dependent manner and induce dendritic cell-mediated Th2/Th17 cell responses”. Journal of Biological Chemistry 288.6 (2013): 4299-4309.
  9. Davitt C.J., et al . “Naturally-derived bacterial nano-particles engage diverse innate receptors, driving the activation of dendritic cells and leading to the establishment of potent adaptive immune responses”. Journal of Immunology 196.1 (2016): 11-76.
  10. Næss LM., et al . “Human T-cell responses after vaccination with the Norwegian group B meningococcal outer membrane vesicle vaccine”. Infection and Immunity 66.3 (1998): 959- 965.
  11. Rosenthal JA., et al . “Mechanistic insight into the T(H)1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles”. PLoS ONE 9.11 (2014): e112802.
  12. Raeven RH., et al . “Immunoproteomic profiling of Bordetella pertussis outer membrane vesicle vaccine reveals broad and balanced humoral immunogenicity”. Journal of Proteome Re - search 14.7 (2015): 2929-2942.
  13. Bottero D., et al . “Characterization of the immune response induced by pertussis OMVs-based vaccine”. Vaccine 34.28 (2016): 3303-3309.
  14. Gaillard ME., et al . “Acellular pertussis vaccine based on outer membrane vesicles capable of conferring both long-lasting immunity and protection against different strain genotypes”. Vaccine 32.8 (2014): 931-937.
  15. Huang W., et al . “Immunization against multidrug-resis - tant Acinetobacter baumannii effectively protects mice in both pneumonia and sepsis models”. PLoS ONE 9.6 (2014): e100727.
  16. Choi SJ., et al . “Active immunization with extracellular vesi - cles derived from Staphylococcus aureus effectively protects against staphylococcal lung infections, mainly via Th1 cell- mediated immunity”. PLoS ONE 10.9 (2015): e0136021.
  17. Daum RS., et al . “Progress toward a Staphylococcus aureus vaccine”. Clinical Infectious Diseases 54.4 (2012): 560-567.
  18. Van der Pol L., et al . “Outer membrane vesicles as platform vaccine technology”. Biotechnology Journal 10.11 (2015): 1689-1706.

Copyright: © 2018 Cinzia Giagulli. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Member In






News and Events

  • Submission Timeline
    Last date for submission of articles is June 30, 2019.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Papers of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US