TE Taranushenko* and NV Matyskina

Department of Pediatrics of Institute of Postgraduate Education, Krasnoyarsk State Medical University Named After Professor Voino-Yasenetsky, Institute of Postgraduate Education for Pediatricians, Krasnoyarsk, Russia

*Corresponding Author: TE Taranushenko, Department of Pediatrics of Institute of Postgraduate Education, Krasnoyarsk State Medical University Named After Professor Voino-Yasenetsky, Institute of Postgraduate Education for Pediatricians, Krasnoyarsk, Russia.

Received: June 16, 2022; Published: July 04, 2022

Abstract

The purpose of the study to analyze the indicators of sonographic examination of the liver and spleen with an assessment of portal hemodynamics in children born to women with syphilitic infection and to identify the most significant signs accompanying early congenital syphilis in the neonatal period.The paper analyzes the data of a comprehensive examination of 397 newborns who were under observation from birth to 1 month of life, included in the studies with an indication of the fact, born to women with a documented history of syphilitic infection.Based on the total sample, three groups of children were formed from birth to 28 days of life, taking into account Federal Clinical guidelines for the management of patients with syphilis (Moscow, 2015)

• Group 1: 114 newborns with early congenital syphilis (RVS) with symptom
• Group 2: 117 patients with early congenital latent syphilis
• Group 3: 166 newborns with specific treponemal antibodies as a consequence of transplacental transfer.

In observation groups 1 and 2, a significant increase in the oblique vertical size of the right lobe was revealed - 74.3 ± 0.7 mm. (p < 0.05) and 73.9 ± 0.4mm (p < 0.05), against 68.8 ± 0.3 mm in the control, as well as the thickness of the left lobe of the liver - 35.3 ± 0.4 mm. (p < 0.05) and 34.8 ± 0.6 mm. (p < 0.05), versus 31.4 ± 0.7 mm. in the control group. Along with this, in these groups, a higher indicator of the maximum blood flow rate in the portal vein was noted, which in these 1 and 2 groups was 0.26 ± 0.02 m/sec (p < 0.05) and 0.25 ± 0.02 m/sec (p < 0.05), respectively, against 0.20 ± 0.02 m/sec in the control. Along with sonographic signs, there was a significant prevalence of hyperbilirubinemia in groups 1 and 2 of newborns - 24.1% (p < 0.001) and 19.9%, respectively, against 9.0% in the control group (neonatal hepatitis was diagnosed in 11.4% of newborns with early congenital syphilis).

Ultrasound features of the liver and in early congenital syphilis should include an increase in size, structural changes in the liver (only with RVS with symptoms) and hemodynamic features characterized by increased blood flow due to an increase in the absolute value of linear velocities (maximum systolic and minimum diastolic) with a reduced resistance index.

Keywords:Early Congenital Syphilis; Newborn; Ultrasonographic Examination

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Citation

Citation: TE Taranushenko and NV Matyskina. “Sonographic Features of The Liver and Spleen in Newborn Children with Early Congenital Syphilis". Acta Scientific Gastrointestinal Disorders 5.8 (2022): 10-17.

Copyright

Copyright: © 2022 TE Taranushenko and NV Matyskina. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.