Alaa Moustafa Attia*

Department of Basic and Clinical Oral Sciences, Division of Periodontology, Faculty of Dentistry, Umm Al-Qura University (Makkah), Saudi Arabia, and Faculty of Dentistry, AL-Azhar University (Assiut), Egypt

*Corresponding Author: Alaa Moustafa Attia, Department of Basic and Clinical Oral Sciences, Division of Periodontology, Faculty of Dentistry, Umm Al-Qura University (Makkah), Saudi Arabia, and Faculty of Dentistry, AL-Azhar University (Assiut), Egypt.

Received: March 08, 2023; Published: March 22, 2023

Abstract

Background: The impact of periodontal infection on several systemic diseases and conditions have been a wide range of recent investigations. The association between periodontitis and cardiovascular diseases (CVD) become established and mostly studied. Thus, periodontal pathogens can cause bacteremia, increased expression of pro-inflammatory proteins leading to vascular infection and development of CVD.

Objectives: The present systematic review aimed to discuss the major ischemic cardiac biomarker; cardiac troponins (cTn) I and T in linking to systemically healthy and periodontitis subjects, and periodontally affected CVD patients.

Materials and Methods: A literature search was presented using two databases (PubMed and Medline), in addition to searching on original articles. The search policy used the combination of the terms: ‘‘Troponin,’’ ‘‘Periodontitis,’’. The result of searching obtained 21 studies, the interested selected studies are 8/21, the selection of these articles based on troponin levels (cTnI and cTnT) in clinical healthy individuals, chronic periodontitis (CP) and CVD patients with periodontitis.

Results: The selected research articles demonstrated that the troponin levels were significantly higher in the periodontitis groups compared to the controls. the troponin levels were highly significantly increased in coronary heart disease patients with periodontitis and the severity of myocardial problems are associated with severity of periodontitis. Moreover, The cTnI more studied in comparison to cTnT in different patient groups. Only one study revealed insignificant differences of cTnI in CP patients after periodontal therapy.

Conclusion: The current review concluded that a strong association between periodontitis and CVD and high troponin levels in periodontally affected CVD patients, and the relation in both diseases is association more than causation. Furthermore, the strategic plan for awareness and prevention of periodontal infections in CVD patients and the effectiveness of nonsurgical periodontal therapy on troponin levels are recommended.

Keywords: Troponins; Periodontitis; CVD; Periodontitis; Periodontal Therapy

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Citation

Citation: Alaa Moustafa Attia. “Troponins as a Major Cardiac Biomarkers and Periodontitis: Systematic Review".Acta Scientific Dental Sciences 7.4 (2023): 66-72.

Copyright

Copyright: © 2023 Alaa Moustafa Attia. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.