Acta Scientific Dental Sciences

Review ArticleVolume 2 Issue 6

An Insight in to Photodynamic Therapy

Laljyothi S1*, Ambili R2, Seba Abraham3, Arunima PR2 and Reeja Mol MK4

13rdYear PG Student, PMS College of Dental Science and Research, Trivandrum, India
2Associate Professor, Department of Prosthodontics, University of Tennessee Health Science Center, Memphis, Tennessee, USA
3Professor and HOD, PMS College of Dental Science and Research, Trivandrum, India
4Reader, PMS College of Dental Science and Research, Trivandrum, India

*Corresponding Author: Laljyothi S, 3rd Year PG Student, PMS College of Dental Science and Research, Trivandrum, India.

Received: April 18, 2018;Published: May 26, 2018

Citation: Laljyothi S., et al. “An Insight in to Photodynamic Therapy”. Acta Scientific Dental Sciences 2.6 (2018).


  Periodontitis is the chronic inflammation of supporting structures of teeth and is the major reason for tooth loss. The objective of periodontal therapy is to reduce the bacterial burden. Non-surgical therapy is considered as the gold standard technique of periodontal therapy. Phototherapy using low level lasers is called photodynamic therapy. Photodynamic therapy targets the specific pathogen without damaging the host tissue. This is effective for killing drug resistant pathogens and in treating multidrug resistant infection. Photodynamic therapy has three different components i.e. light, photosensitizer and oxygen. There are two mechanisms in antimicrobial photodynamic therapy. One is DNA damage and the second method is damage to the bacterial cytoplasmic membrane resulting in inactivation of the membrane transport system, inhibition of plasma membrane enzyme activities, lipid peroxidation and others. In photodynamic therapy bacterial killing is mainly by damaging the cytoplasmic membrane of bacteria. It has different applications in various fields of dentistry. In periodontics it is used for treating both periodontitis and periimplantitis. The adjunctive use of PDT to scaling and root planning in the treatment of patients with chronic periodontitis, aggressive periodontitis and periimplantitis, resulted in greater clinical attachment level gains, reduction in bleeding on probing and probing pocket depths. The aim of this review is to describe briefly about the photodynamic therapy and its uses and evidences in periodontics and implant dentistry.

Keywords: Periodontitis; Anti-Microbial Photodynamic Therapy; Photosensitizer Dye; Management of Periimplantitis; Laser Light

Copyright: © 2018 Laljyothi S., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Member In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for March Issue
    The last date for submission of articles for regular Issues is February 29, 2020.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US