Meghna Garg, Anubhuti Sharma* and PK Rai
Senior Scientist (Biochemistry), ICAR-DRMR, Bharatpur, (Rajasthan), India
*Corresponding Author: Anubhuti Sharma, Senior Scientist (Biochemistry), ICAR-DRMR, Bharatpur, (Rajasthan), India.
Received: November 25, 2019; Published: January 18, 2020
Various biologically active compounds present in mustard have proved as potential anti-cancerous agents. Sinigrin inhibits angiogenesis and reduces inflammation in tumors. Phenethyl isothiocyanates (PEITC) induces apoptosis in Jurkat T-lymphoma cells overexpressing the oncoprotein Bcl-2. Sulforaphane inhibits cell proliferation and metastasis, block the action of mutagens and induces apoptosis of the transformed cells. High selenium mustard can help in curing breast and prostate cancer. Mustard seeds rich diet has been shown to prevent colon, skin and cervix cancer in animal model. Benzyl isothiocyanate (BITC) suppresses pancreatic tumor growth and angiogenesis. The following review tried to throw light on the mechanism of action and experimental studies conducted on the same.
Keywords: Sinigrin; Cancer; Mustard
Citation: Anubhuti Sharma., et al. "Sinigrin: A Cancer Preventing Agent".Acta Scientific Cancer Biology 4.2 (2020): 01-05.
Copyright: © 2020 Anubhuti Sharma., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.