Lucas Ribeiro dos Santos*
Department of Endocrinology and Physiology. Faculty of Medical Sciences of Santos - UNILUS – Santos, São Paulo, Brazil
*Corresponding Author: Lucas Ribeiro dos Santos, Department of Endocrinology and Physiology. Faculty of Medical Sciences of Santos - UNILUS – Santos, São Paulo, Brazil.
Received: November 25, 2019; Published: December 02, 2019
Hyperthyroidism is a rather common disease, with prevalence rates, In the United States, of approximately 1.2% of the population ; diffuse toxic goiter, otherwise denominated Grave ́s disease (GD), is the most common cause of hyperthyroidism globally , but its association with thyroid papillary carcinoma remains uncertain.
While the incidence of thyroid malignancies rises in the whole world, reaching escalating numbers of 7% to 15% of the patients harboring a nodule, depending on age, sex, family history, and other factors [3,4], the malignancy rate of palpable thyroid nodules in GD patients ranges from 2% to up to 55% [5,6].
Current case series and cohorts rise even more questions regarding the aggressiveness of thyroid cancers in GD patients. Aggressive behavior has been identified by some reports, including increased rates of para-thyroidal invasion and lymphatic metastasis [6-8]. Mortality rates seems to also be higher in GD patients, and that remains a fact independently of tumor size [9-11], though this has not been confirmed by other case series [12,13].
Citation: Lucas Ribeiro dos Santos. 02Is Grave ́S Disease A Risk Factor for Papillary Thyroid Carcinoma? Should We Be Actively Screening?.Acta Scientific Cancer Biology 4.1 (2020): 01-02.
Copyright: © 2020 Lucas Ribeiro dos Santos. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.