Acta Scientific Cancer Biology (ASCB)

Mini Review Volume 4 Issue 2

Chemotherapy Safety Insurance Using Extracorporeal Detoxification Methods

Voinov VA*, Orlov SV, Karchevsky KS, Isaulov OV and Voinova Ya V

First St. Petersburg State Medical University, Russia

*Corresponding Author: Voinov VA, First St. Petersburg State Medical University, Russia.

Received: December 11, 2019; Published: January 07, 2020

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Abstract

   High-dose chemotherapy for malignant tumors is accompanied by severe endotoxemia with damage to various organs and systems. This often forces to interrupt the course of treatment, which discounts its results. Conventional infusion therapy is not able to remove high molecular weight endotoxins, the kidneys do not remove them and the liver does not destroy them either. Extracorporeal detoxification using plasmapheresis and hemosorption helps eliminate these complications, which opens the possibility of using higher doses of chemotherapy and improve the treatment outcomes. The article describes the clinical observation in a patient with inoperable ovarian cancer, when using this treatment it was possible to extend life from half a year to four years.

Keywords: Cancer Chemotherapy; Endotoxemia; Extracorporeal Detoxification; Plasmapheresis; Hemosorption

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Citation

Citation: Voinov VA., et al. “Chemotherapy Safety Insurance Using Extracorporeal Detoxification Methods”.Acta Scientific Cancer Biology 4.2 (2020): 01-03.



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