Acta Scientific Cancer Biology (ASCB) (ISSN: 2582-4473)

Research Article Volume 7 Issue 4

Clinical and Demographic Profile of Geriatric Patients in Eastern India

Seema Devi1*, Rajesh Kumar Singh2, Abhishek Kumar3, Raina Rana4 and Aman Prakash5

1Additional Professor, State Cancer Institute, Department of Radiation Oncology, IGIMS, Patna, India
2Professor and HOD, State Cancer Institute, Department of Radiation Oncology, IGIMS, Patna, India
3PG 3rd Year, Department of Radiation Oncology, IGIMS, Patna, India
4PG 2nd Year, State Cancer Institute, Department of Radiation Oncology, IGIMS, Patna, India
5Statistician, State Cancer Institute, Department of Radiation Oncology, IGIMS, Patna, India

*Corresponding Author: Seema Devi, Additional Professor, State Cancer Institute, Department of Radiation Oncology, IGIMS, Patna, India.

Received: May 08, 2023; Published: May 30, 2023


Background Information: A person who is of age of 60 years or above defined as elderly or senior citizen, citizen of India. As per maintenance and welfare of patients and senior citizen Act 2007 (1) Older population is rapidly increasing in most of the countries. This increase in older population has created new field of medicine “Gerontology”.

Material and Method: A retrospective analysis has been done in State Cancer Institute Patna for year 2014 to 2021. Cut-off age was kept as 85 years at the time of registration in Hospital based Registry Programme. All the biopsy proven cases either by FNAC or Biopsy proven were included.

Result: In our study total cases registered 32057 from year 2014 to 2021 6830 patients were registered from age 60 years to 85 years, which were 25.88% of total cancer patients. In year wise distribution 922(8.1%) cases were registered in 2014, 1188 (10.4%) cases in 2015, 1513(13.35%) in 2016, 2258(19.93%) in 2017, 2061 (18.19%) in 2018, 665(5.8%) in 2019,1284(11.33%) cases in 2020,1437 12.8% cases in 2021 were registered in this age group.

Conclusion: Screening and early detection may help to reduce the severity of disease like gallbladder, head and neck carcinoma, carcinoma cervix. Treatment with comorbidities like diabetes, hypertension, chronic obstructive pulmonary disease, low nutritional level are the barriers to provide, curative treatment in this age group of patients.

 Keywords: Gerontology; Cancer; Geriatrics; Clinical Profile


  1. “Maintenance and Welfare of Parents and Senior Citizens Act” (2007).
  2. Yeole BB., et al. “Geriatric cancers in India: an epidemiological and demographic overview”. Asian Pacific Journal of Cancer Prevention 2 (2008): 271-274.
  3. Elderlyin in India.
  4. Harding C., et al. “Cancer Suppression at Old Age”. Cancer Research 68 (2008): 4465-4478.
  5. Saltzstein SL., et al. “Features of cancer in nonagenarians and centenarians”. Journal of the American Geriatrics Society 46 (1998): 994-998.
  6. Pompei F and Wilson R. “Age distribution of cancer. The incidence turnover at old age”. Human and Ecological Risk Assessment 7 (2001): 1619-1650.
  7. Alterovitz SS and Mendelsohn GA. “Relationship goals of middle-aged, young old, and old-old Internet daters: an analysis of online personal ads”. Journal of Aging Studies 27 (2013): 159-165.
  8. Choudhury KB., et al. “Upward trend of geriatric patients in oncology at a tertiary health care centre”. International Journal of Research and Review6 (2020): 168-175.
  9. Yancik R. “Population aging and cancer: a cross-national concern”. Cancer 11 (2005): 437-441.
  10. Bosch FX., et al. “Primary liver cancer: Worldwide incidence and trends”. Gastroenterology 127 (2004): S5-S16.
  11. Ferlay I. Soerjomatatara Cancer Incidence an Ervik M., et al. GLOBOCAN 2012 v10 Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 11. Lyon, France: International Agency for Research on Cancer (2013).
  12. Estape T., et al. “Knowledge and attitudes towards cancer in an old sample: Final report”. Psycho-Oncology 22 (2013): 172-173.
  13. Berger KS. “The Developing Person Through the Life”. 7th Edition (Spanish Version) Editorial Médica Panamericana. SA. Mádrid (2014).
  14. Marosi C and Koller M. “Challenge of cancer in the elderly”. ESMO Open3 (2016): e000020.
  15. Zongli Xu., et al. “Genome-wide age-related DNA methylation changes in blood and other tissues relate to histone modification, expression and cancer”. Carcinogenesis2 (2014): 356-364.
  16. Aunan JR., et al. “The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks”. Aging Disease5 (2017): 628-642.
  17. Patil V M., et al. “Patterns of care in geriatric cancer patients – An audit from a rural based hospital cancer registry in Kerala”. Indian Journal of Cancer 52 (2015): 157-161.
  18. Mohile S., et al. “Geriatric oncology research to improve clinical care”. Nature Reviews Clinical Oncology 10 (2012): 571-578.
  19. Diehl AK. “Epidemiology of gallbladder cancer: A synthesis of recent data”. Journal of the National Cancer Institute 65 (1980): 1209-1214.
  20. Kapoor R., et al. “Pattern of cancer in Jammu region (hospital based study 1978-87)”. Indian Journal of Cancer 30 (1993): 67-71.
  21. Sikora SS., et al. “Palliative surgical treatment of malignant obstructive jaundice”. European Journal of Surgical Oncology 20 (1994): 580-584.
  22. Harman D. “The free radical theory of aging”. Antioxidants and Redox Signaling 5 (2003): 557-561.
  23. NCRP (2021).
  24. Francis CJK. “Trends in incidence of head and neck cancers in India”. ESMO Asia 2016 Congress. Aetiology, Epidemiology, Screening and Prevention Head and Neck Cancers (2016).
  25. Surveillance Epidemiology and End Results (SEER): SEER Cancer Statistics Review, 1975-2015.
  26. Subramaniam NR., et al. “Radical radiotherapy for carcinoma of the larynx in the elderly: Functional and oncological outcomes from a tertiary cancer care center in India”. Indian Journal of cancer3 (2017): 493-497.
  27. Suhag V., et al. “Radiotherapy and geriatric cancer patients: A single institute experience”. Indian Journal of Medical Sciences 1 (2019): 28-34.
  28. Smith PW and Jones DR. “Biology and epidemiology of lung cancer”. in: Patterson GA, Cooper JD, Deslauriers J, et al. eds. Pearson’s Thoracic and Esophageal Surgery. 3rd Philadelphia, PA: Churchill Livingstone Elsevier, (2008): 708-728.
  29. Owonikoko TK., et al. “Lung cancer in elderly patients: an analysis of the surveillance, epidemiology, and end results database”. Journal of Clinical Oncology 25 (2007): 5570-5577.
  30. Cancer research UK. “Lung cancer incidence statistics”. (2016).
  31. Meyer KC. “Lung infections and aging”. Ageing Research Reviews 3 (2004): 55-67.
  32. Verra F., et al. “Ciliary abnormalities in bronchial epithelium of smokers, ex-smokers, and non-smokers”. American Journal of Respiratory and Critical Care Medicine 151 (1995): 630-634.
  33. Salathe M., et al. “Treatment of mucociliary dysfunction”. Chest 110 (1996): 1048-1057.
  34. US National Institutes of Health Cancer of the cervix uteri (2005).
  35. Hsang HJ., et al. “Prognostic value of age and Histology type in neoadjuvant chemotherapy plus radical surgery for bulky (>/=24 cm) stage IB and IA cervical carcinoma”. International Journal of Gynecological Cancer 2 (2003): 204-211.
  36. Kastritis E., et al. “The impact of age in the outcome of patients with advanced or recurrent cervical cancer after platinum-based chemotherapy”. Gynecologic Oncology2 (2007): 372-376.
  37. Torre LA., et al. “Global cancer statistics, 2012”. CA: A Cancer Journal for Clinicians 2 (2015): 87-108.
  38. Xu XS., et al. “Survival analysis of hepatocellular carcinoma: a comparison between young patients and aged patients”. Chinese Medical Journal (Engl)13 (2015): 1793-1800.
  39. Kondo K., et al. “Hepatic resection is justified for elderly patients with hepatocellular carcinoma”. World Journal of Surgery10 (2008): 2223-2229.
  40. Liver EA for the S of the, Cancer EO for R and T of. “EASL-EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma”. Journal of Hepatology4 (2012): 908-943.
  41. GLOBOCAN (2020).
  42. International Agency for Research on Cancer. India Source: Globocan (2020).
  43. National Cancer Registry Programme. Three-year report of the population-based Cancer Registries, 2012-2014. Indian Council of Medical Research, Bangalore (2016).
  44. Maurya AP and Bramhachari S. “Current status of Breast Cancer Management in India”. Indian Journal of Surgery (2020).
  45. Global Burden of Disease Cancer Collaboration. “Global, regional, and national cancer incidence, mortality, years of life lost. years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: a systematic analysis for the Global Burden of Disease Study”. JAMA Oncology 5 (2019): 1749-1768.
  46. Lim JH., et al. “Clinicopathological features and surgical safety of gastric cancer in elderly patients”. Journal of Korean Medical Science 29 (2014): 1639-1645.
  47. Joharatnam-Hogan N., et al. “Challenges in the treatment of gastric cancer in the older patient”. Cancer Treatment Reviews 85 (2020): 101980.
  48. Saif MW., et al. “Gastric cancer in the elderly: an overview”. European Journal of Surgical Oncology 36 (2010): 709-717.
  49. Matthaiou C and Papamichael D. “Management of gastric cancer in older adults”. Journal of Geriatric Oncology 8 (2017): 403-406.
  50. Crowford ED. “Epidemiology of prostate cancer”. Urology 62 (2003): 3-12.
  51. Femal A., et al. “Cancer statistics, 2007”. CA: A Cancer Journal for Clinicians 57 (2007): 43-66.
  52. American Cancer Society, authors. Cancer Facts and Figures 2007 Atlanta, GA: American Cancer Society (2007).
  53. “The Department of Defense Center for Prostate Disease Research, authors”. Oncology (Williston Park) 13 (1999): 13:1338-1336.
  54. Newcomer LM., et al. “Temporal trends in rates of prostate cancer: declining incidence of advanced stage disease, 1974 to 1994”. Journal of Urology 158 (1997): 1127-1130.
  55. Carter HB., et al. “Clinical evidence for and implications of the multistep development of prostate cancer”. Journal of Urology 143 (1990): 742-746.
  57. Schmoll HJ., et al. “ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making”. Annals of Oncology10 (2012): 2479-2516.
  58. Smith A., et al. “Incidence of haematological malignancy by sub-type: a report from the Haematological Malignancy Research Network”. Cancer11 (2011): 1684-1692.
  59. J Morton LM., et al. “Lymphoma Incidence patterns by WHO subtype in the United States, 1992-2001”. Blood1 (2006): 265-276.
  60. Central Brain Tumor Registry of the United States: 2009 CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2004-2005 (2010).
  61. Wrensch M., et al. “Epidemiology of primary brain tumors: current concepts and review of the literature”. Neurology Oncology 4 (2002): 278-299.
  62. Iwamoto FM., et al. “Patterns of care in elderly glioblastoma patients”. Annals of Neurology 64 (2008): 628-634.


Citation: Seema Devi., et al. “Clinical and Demographic Profile of Geriatric Patients in Eastern India" Acta Scientific Cancer Biology 7.4 (2023): 12-24.


Copyright: © 2023 Seema Devi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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