We reviewed earlier the importance of human papilloma virus (HPV), in Cervical Cancer development with role of various viral proteins, as well as oropharyngeal cancer [1-2]. Although 90% of HPV infections get cleared within 2yrs without need for medical treatment, persistent infections with HPV’s at high risk (HR- HPV’s) can progress to cancer. Low risk HPV (LR HPV) usually don’t cause cancers but get correlated with genital warts as well as respiratory papillomatosis [3,4]. Besides that other proof correlated HPV with vaginal, vulvar penile, anal along with oropharyngeal Cancer particularly tonsillar, as well as base of tongue [4].

References

1. Kulvinder Kochar Kaur., et al. “A Systematic Review of Aetiopathogenesis of Cervical Cancer Development-Role of HPV, Cervical Cancer Stem Cells and Micro RNA and Utilizing these as Novel Targets for Treatment – An Update”. Acta Scientific Cancer Biology 3.11 (2019): 28-37.
2. Kulvinder Kochar Kaur., et al. “HPV Related Disease and Cancers-Increased incidence of HPV-Positive Oropharyngeal Cancers”. Acta Scientific Microbiology 2.7 2.7 (2019): 1-4.
3. Ho GY., et al. “Natural history of cervicovaginal papillomavirus infection in young women”. The New England Journal of Medicine 338 (1998): 423-428. 
4. Tommasino M. “The human papillomavirus family andits role in carcinogenesis”. Seminars in Cancer Biology 26 (2014): 13-21.
5. Ahrlund-Richter A., et al. “Changes in Cervical human papilloma virus (HPV), prevalence at a youth clinic in Stockholm, Sweden, a Decade After the Introduction of the HPV Vaccine”. Frontiers in Cellular and Infection Microbiology 9 (2019): 59.
6. Schiller J and Lowy D. “Explanations for the high potencyof HPV prophylactic vaccines”. Vaccine 36.32 (2018): 4768-4773.
7. Du J., et al. “Prevalence of human papillomavirus (HPV) types in cervical cancer 2003-2008 in Stockholm, Sweden, before public HPV vaccination”. Acta Oncologica 50 (2011): 1215-1219. 

Citation

Citation: Kulvinder Kochar Kaur. “Editorial-Despite Gardasil 9 Success Not Reached in Complete Eradication of High Risk Human Papilloma Virus-What is the Next Step for Cervical, Oropharyngeal Cancers Prevention". Acta Scientific Cancer Biology 4.2 (2020): 01-02.

Copyright

Copyright: © 2020 Kulvinder Kochar Kaur. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.