Abstract

The present work aimed to investigate the possible effect of beetroot juice to overcome the splenic toxicity diclofenac - induced. 40 male albino mice were divided, 1^st group deal as control group, 2^nd treated with 8ml/kg of freshly prepared beetroot juice, 3^rd treated with oral daily dose 20 mg/kg of diclofenac and 4^th pre-treated with beetroot juice to diclofenac administration. Diclofenac treatment resulted in significant increase of liver and kidney functions, marked pathological alterations as diffusion of white pulp, minimized lymph nodes areas and volumes, increased pathological score, neutrophils and oxidative stress. The pre-treatment of beetroot to diclofenac revealed significant increase in liver and kidney functions, noticeable improvement in the spleen tissue manifested by decreasing of pathological score, neutrophils and oxidative stress.

Keywords: Spleen; Liver; Diclofenac; Beetroot; Pathological Score

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Citation

Citation: Hussah M Alobaid., et al. “Beta vulgaris Impact on Splenic Toxicity Diclofenac-induced in Swiss Albino Mice”. Acta Scientific Women's Health 3.2 (2021): 35-42.

Copyright

Copyright: © 2021 Hussah M Alobaid., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.