Abstract

The antiviral activity of the propolis phenolic fraction of (PPF) against influenza virus, adenovirus and coronavirus and vesicular stomatitis virus was studied. As a result of the performed study the maximum tolerated concentration (MTC) of cell culture of human or animal origin was determined, which was 1.0% for the lot of PPF № 1 and 0.5% for the lot of PPF № 2. An aqueous solution of PPF (lot № 1) decreased coronavirus hemagglutinin titer by 4 - 8 times, thus indicating the prospects of using the drug against coronavirus infections.

Keywords: Propolis Phenolic Fraction; Antiviral Activity; Maximum Tolerated Concentration

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Citation

Citation: Oleg S Shpychak and Payal Chauhan. “Study of the Antiviral Activity of Propolis Phenolic Fraction".Acta Scientific Pharmaceutical Sciences 4.10 (2020): 41-47.

Copyright

Copyright: © 2020 Oleg S Shpychak and Payal Chauhan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.