Acta Scientific Paediatrics (ISSN: 2581-883X)

Research Article Volume 3 Issue 6

HIV Mother to Child Transmission-An Empirical and Cross Sectional Study

Gopalakrishna Mitra1, Asha Benakappa1and Basavarajaiah DM2*

1Department of Pediatrics, Bangalore Medical College and Research Institute, Bangalore, India
2Department of Pediatrics, Bangalore Medical College and Research Institute, Bangalore, India

*Corresponding Author: Basavarajaiah DM, Department of Stat and CS, KVAFSU, India.

Received: March 09, 2020; Published: May 31, 2020

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Abstract

Mother-to-child-transmission of HIV (HIV MTCT) is a major route of HIV infection in children. The literature cited that, the mother to Child transmission of HIV spread from a women living with HIV to her child during pregnancy, childbirth (also called labor and delivery) or of breast feeding (through breast milk). However, more number of study would be necessary for the implement the policy at worldwide. In this paradigm the present study to estimate the HIV transmission rate (HIV mother to child) in association with PMTCT and WHO guidelines on prospective and retrospective basis. A prospective and cross sectional study was conducted in the Department of Paediatrics, Bangalore Medical College and Research Institute during the period of (2013-14). A total 147 ANC’s were recruited with written consent and Institutional ethical clearance was obtained in accordance with stipulated WHO and NACO guidelines. The correlation between the HIV MTCT with or without ARV drug before and after delivery was analysed unpaired t-test, the research was prospectively studied with mean duration 2.5 - 3.0 years. The intervention of MTCT rate was recorded at regular follow up HAART therapy. As per the findings, the MTCT rate was found to be fewer percentage expression who received ARV drug before after pregnancy and results was found to be statistically significant differ (p < 0.01, chi-square 13.52; odd ratio 1.5 - 2.21) when compare to without ARV drugs. The mean CD4 count with ARV drug was 308 micro/dl and in case of without ARV mean CD4 count was 385.52 micro/dl. The infection rate was estimated with and without ARV it was found to be (5.74%) and (23.33%) respectively besides with WHO clinical stage III and IVth respectively. The present study concludes that, the strengthen the PMTCT guidlines to reduce the transmission risk of HIV MTCT. Abensece of ARV drug increase the transmssion rate at five fold more likely to transmit the disease.

Keywords: MTCT; PMTCT; HIV; AIDS; ARV

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Citation

Citation: Basavarajaiah DM., et al. “HIV Mother to Child Transmission-An Empirical and Cross Sectional Study”. Acta Scientific Paediatrics 3.6 (2020): 40-44.



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