Acta Scientific Paediatrics (ISSN: 2581-883X)

Case Report Volume 3 Issue 6

Immune Thrombocytopenic Purpura Secondary to Coronavirus Infection

Ahmad Hachem, Dima Habanjar, Reem Abdelnabi and Rana Sharara-Chami*

Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon

*Corresponding Author: Rana Sharara-Chami, Associate Professor of Pediatrics and Pediatric Critical Care, Director, Pediatric Residency Program, Director, Simulation Program, Department of Pediatrics and Adolescent Medicine. Research Associate, Boston Children's Hospital, Harvard Medical School, Boston, MA and American University of Beirut Medical Center, Beirut, Lebanon.

Received: March 04, 2020; Published: May 19, 2020

×

Abstract

 Our patient is a 2-year-old previously healthy boy presenting with fever and a generalized rash. A completed blood count at his initial presentation showed a platelet count of 29,000 cu.mm. He was found to have coronavirus 229 E on the respiratory viral panel by multiplex PCR.

Keywords: Immune Thrombocytopenic Purpura (ITP); Coronavirus Infection; Epstein-Barr Virus

×

References

  1. ITP A. “Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy”. British Journal of Haematology 1 (2003): 574-596.
  2. McMillan R., et al. “Prospective evaluation of the immunobead assay for the diagnosis of adult chronic immune thrombocytopenic purpura (ITP)”. Journal of Thrombosis and Haemostasis3 (2003): 485-491.
  3. Semple J. “Immune pathophysiology of autoimmune thrombocytopenic purpura”. Blood Reviews1 (2002): 9-12.
  4. Zhou B., et al. “Multi-dysfunctional pathophysiology in ITP”. Critical Reviews in Oncology/Hematology2 (2005): 107-116.
  5. Filion MC., et al. “Presence in peripheral blood of healthy individuals of autoreactive T cells to a membrane antigen present on bone marrow-derived cells”. Blood 6 (1996): 2144-2150.
  6. Liu B., et al. “Abnormality of CD4+ CD25+ regulatory T cells in idiopathic thrombocytopenic purpura”. European Journal of Haematology2 (2007): 139-143.
  7. Nimmerjahn F and JV Ravetech. “Fcꭚ receptors as regulators of immune responses”. Native Reviews Immunology1 (2008): 34.
  8. Lee CY., et al. “Acute immune thrombocytopenic purpura in an adolescent with 2009 novel H1N1 influenza A virus infection”. Journal of the Chinese Medical Association9 (2011): 425-427.
  9. Tilden W and S Valliani. “Severe thrombocytopenia and recurrent epistaxis associated with primary Epstein-Barr virus infection”. Case Reports (2015).
  10. Flores-Chang BS., et al. “Immune thrombocytopenic purpura secondary to cytomegalovirus infection: a case report”. Frontiers in Medicine 2 (2015): 79.
  11. George JN., et al. “Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology”. Blood1 (1996): 3-40.
  12. Provan D., et al. “International consensus report on the investigation and management of primary immune thrombocytopenia”. Blood 2 (2010): 168-186.
  13. Stasi R and D Provan. “Management of immune thrombocytopenic purpura in adults”. In Mayo Clinic Proceedings (2004).
  14. Rodeghiero F., et al. “Treatment practices in adults with chronic immune thrombocytopenia - a European perspective”. European Journal of Haematology 2 (2010): 160-168.
×

Citation

Citation: Rana Sharara-Chami., et al. “Immune Thrombocytopenic Purpura Secondary to Coronavirus Infection”. Acta Scientific Paediatrics 3.6 (2020): 19-22.



Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is November 10, 2020.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US