Although vaccines have been quiet successful in reducing the large burden of serious infections. Neonates still remain quiet vulnerable to life-threatening infections. They take their greatest toll during the early stages of life. Hence various approaches are required to protect them. Here we review the rationale, current state, and research for such approach i.e neonatal immunization. There are many challenges to neonatal immunization. Few of them include concern regarding the safety of the vaccine and distinct neonatal immune system (vaccines which are effective in adults are not effective in new borns). Despite distinct neonatal immunity, there are several vaccines which have proven safe and effective at birth. However neonatal immunization at birth is quiet a reliable point of healthcare contact, so is an opportunity for early protection of neonates against diseases, including preterms which are deficient in passively transferred maternal antibodies. While some vaccines such as polysaccharide vaccines have little effectiveness at birth, hepatitis B vaccine can prime at birth and requires multiple doses to achieve protection, contrary to the BCG vaccine which, offers single shot protection.

Keywords: Neonatal; Vaccine; Protection; Immunity

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Citation

Citation: Richa Sharma. “Neonatal Immunization”. Acta Scientific Paediatrics 3.2 (2020): 57-58.

Copyright

Copyright: © 2020 Richa Sharma. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.