Abstract

  The top objective of any pharmaceutical industry is to produce products of necessary characteristic and quality in a cost-effective manner. Analytical method development is essential for discovery, development, and evaluation of medicines in the pharmaceutical formulation. It helps in ensuring the safety and efficacy of drugs in different matrices by determining the quantity and quality of Drug. In Research activities literature survey is the vital requirement. Mupirocin belongs to the class of topical antibacterial agent, which is a natural crotonic acid that is extracted from a strain of Pseudomonas fluorescens. It works by inhibiting bacterial protein synthesis by specifically and reversibly binding to bacterial isoleucyl tRNA synthase which is an enzyme that promotes conversion of isoleucine to isoleucyl tRNA. It is used for treatment of primary and secondary skin disorder like impetigo, nasal infection and wound healing. In this article main prominence is given on the various techniques which are used for the estimation of the Mupirocin from various Pharmaceutical dosage forms. Among various methods generally UV and HPLC are the most widely used techniques. Various validation parameters used for method development are being figure out in the article.

Keywords: Mupirocin; Analytical Methods; Antibacterial Agent; Matrices; Estimation

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Citation

Citation: Sapra Ritu., et al. “In Depth Investigation of Analytical Methods for the Estimation of Antibacterial Drug Mupirocin in Different Matrices: A Review".Acta Scientific Pharmacology 1.10 (2020): 36-43.

Copyright

Copyright: © 2020 Sapra Ritu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.