Abstract

  Spondyloarthropathy (SpA) connotes sero-negative spondyloarthropathy implying absence of rheumatoid factor. SpA is a group of overlapping disorders of chronic inflammatory diseases of autoimmune nature sharing certain clinical features and common genetic associations with HLA-B27 [1]. Broadly, it is grouped as axial spondyloarthropathy and peripheral arthropathy.

  The peripheral spondyloarthropathy has a certain pattern of peripheral joint involvement, usually asymmetric mono arthritis or oligo arthritis affecting major joints of lower extremities. Peripheral SpA encompasses psoriatic arthropathy, associated with inflammatory bowel disorder (i.e. Crohn’s disease and ulcerative colitis), associated with anterior uveitis, reactive arthritis (Reiter’s Disease). Sometimes to start with, it can not be differentiated into a particular pattern and hence, is called undifferentiated spondylarthritis. Similar presentation in children is aptly coined as juvenile spondyloarthropathy. Enthesitis and dactylitis are commonly associated extra-articular manifestations in this group, apart from axial involvement.

References

1. Poddubnyy D. “Axial spondyloarthritis: is there a treatment of choice?” Therapeutic Advances in Musculoskeletal Disease 5.1 (2013): 45-54. 
2. Ruben BV. “The assessment of the spondyloarthritis international society concept and criteria for the classification of axial spondyloarthritis and peripheral spondyloarthritis: A critical appraisal for the pediatric rheumatologist”. Pediatric Rheumatology 10 (2012):14.
3. Rudwaleit M et al. Annals of the Rheumatic Diseases 68 (2009): 777-783. 

Citation

Citation: SS Jha. "Transition of axial spondyloarthropathy in to Ankylosing Spondylitis".Acta Scientific Orthopaedics 3.1 (2020): 16-17.

Copyright

Copyright: © 2020 SS Jha. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.