Abstract

Introduction: Parathyroid adenoma is the common cause of Primary hyperparathyroidism. It is a benign solitary tumor of parathyroid gland. It is a very rare tumor and has very nonspecific clinical symptoms.

Objective: 1) To arrive at correct diagnosis of parathyroid adenoma in patient with clinically non-specific symptoms by biochemical and radiological investigation and final confirmation by histopathological examination. 2) This study assesses the impact of excision of parathyroid adenoma and patient outcomes with a great quality of life.

Methods: We conducted a retrospective interventional case analysis by selecting 10 patients with biochemically and radiologically proven to be parathyroid adenoma who came to Civil Hospital, Ahmedabad referred from orthopaedic and medicine department from period of July 2018 to October 2019 who underwent surgical excision and had post-operative histological and biochemical confirmation.

Result:  1) There were 10 operated cases of parathyroid adenoma at our institute in last one year. 2) Out of which 10 were symptomatic and one case detected incidentally. Symptoms were varied and included skeletal, renal, neuromuscular and neuropsychiatric manifestation. 3) Histopathologically, out of 10 operated cases, 9 cases proven to be benign parathyroid adenoma while one case suggests possibility of malignancy.

Conclusion: 1) Majority of cases were female presented with neuromuscular, neuropsychiatric symptoms, some of cases had renal symptoms. There was even one incidental case of asymptomatic parathyroid adenoma. 2) In all these cases, 10 cases had high clinical suspicion which was aided by biochemical finding and was followed by tc99 sestamibi scan which help in confirming diagnosis of parathyroid adenoma which was subsequently proved by histopathological examination. 3) There was definitive indication of surgery in all these cases and symptomatic improvement was noted after the surgery was performed.

Keywords: Parathyroid Gland; Parathyroid Adenoma; Hypercalcemia; Primary Hyperparathyroidism; Renal Stone

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Citation

Citation: Vaishali A Patel., et al. “A Case Series of Parathyroid Adenoma: Our Institute Experience". Acta Scientific Otolaryngology 2.5 (2020): 19-24.

Copyright

Copyright: © 2020 Vaishali A Patel., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.