Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Case Report Volume 4 Issue 8

Non Waldenstrom Macroglobulenemia Igg Secreting Lymphoplasmacytic Lymphoma - A Diagnostic Challenge

Himanshu Rohela1*, Sameer Tulpule2, Nevitha Athikhari3, Deepthi Murthy4 and Raj H Vhatkar1

1Department of Orthopaedic Oncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India
2Department of Haematooncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India
3Department of Histopathology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India
4 Department of Histopathology, Dr Lal Path Paths, National Reference Laboratory, Delhi, India

*Corresponding Author: Himanshu Rohela, Department of Orthopaedic Oncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India.

Received: May 20, 2020; Published: July 28, 2020

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Abstract

 Lymphoplasmacytic lymphoma (LPL) is a low-grade, B-cell neoplasm composed of small lymphocytes, plasmacytoid lymphocytes, and plasma cells that typically involve the bone marrow, and it is associated with an immunoglobulin M (IgM) gammopathy. The diagnosis of LPL itself can be challenging because LPL lacks disease-specific morphologic, immunophenotypic, and genetic features to differentiate it from other mature B-cell neoplasms. Although most cases of LPL are IgM secreting, there are exceptions of rare, primary, lymph node-based presentations of LPL or lymphoplasmacytic B-cell proliferations in the bone marrow associated with IgA or IgG gammopathies. We hereby report a case of IgG secreting lymphoplasmacytic lymphoma under our tracking and review of the related literature on management of this rare tumor.

Keywords: Waldenstrom Macroglobulinemia (WL); Lymphoplasmacytic Lymphoma (LPL)

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References

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Citation

Citation: Himanshu Rohela., et al. “Non Waldenstrom Macroglobulenemia Igg Secreting Lymphoplasmacytic Lymphoma - A Diagnostic Challenge". Acta Scientific Medical Sciences 4.8 (2020): 107-110.




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Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor0.851

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