Materials and Method: Dried and pulverized papaya roots were mixed with extraction solvents (water and ethanol). Aseptically the extracts were filtered and inoculated into Nutrient agar to ascertain sterility of the solutions.

Results: Results showed high antibacterial activity for ethanol extract and the cold-water extract of Carica papaya with ethanol extract having more effect. It was observed that the extract was effective against the Gram- positive and Gram-negative test organisms investigated while the Antibiotic susceptibility test revealed that the microorganisms were resistant to one or two of the antibiotics used (Ceftazidime (30 μg), Cefuroxime (30 μg), Gentamicin (10 μg), Ciprofloxacin (5 μg), Augmentin (50 μg), Nitrofurantoin (300 μg), Oflaxacin (5 μg), Ampicillin (10 μg) except for Escherichia coli which was resistant to all antibiotics used.

Conclusion:From the results obtained in this study, it can be inferred that Carica papaya root part is a potential source of natural therapeutic option that can be further exploited for the treatment of bacterial infection.

Keywords: Carica papaya; Antibacterial; Pathogenic Bacterial Isolates; Extracts

Copyright: © 2018 Wemambu Ifeoma Irene., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.