Abstract

 The percentage of liver transplantations over the last two decades has been on the rise across the world, nearly 33000 reported transplants took place in 2017 with an increase expected in the upcoming years. Majority of the recipients of liver transplant generally has liver cirrhosis caused by NAFLD/AFLD making them vulnerable to damage their other organs as well. In most cases the transplantation organ is donated by a blood relative within the family as most other donors have high chances of graft rejection. We report a case of liver cirrhosis patient with continuously liver function tests carried out for a period of three months, subsequently the patient was listed as one of the recipients for liver transplant as his biochemical parameters showed signs of liver failure progressing to severe state.

Keywords: NAFLD; AFLD; Liver Cirrhosis; Liver Function Tests

References

1. Asrani SK., et al. “Burden of liver diseases in the world”. Journal of Hepatology1 (2019): 151-171.
2. Perri GA and Khosravani H. “Complications of end-stage liver disease”. Canadian Family Physician 62 (1): 44-50.
3. Aslam F and Kulasena H. “To identify and examine the different causes of liver disease in Sri Lanka”. Indian Journal of Scientific Research (2017).
4. Aslam F and Kumarasinghe N. “Serum Creatinine Level and Its Relation to Backache in Chronic Kidney Disease with Unknown Aetiology (CKDu) Patients in North Central Province, Sri Lanka” (2018).
5. Kiuchi T., et al. “Living-donor liver transplantation in Kyoto, 1997”. Clinical Transplants (1997): 191-198.
6. Manyalich, M., et al. “EULID project: European living donation and public health”. Transplantation Proceedings 6 (2009): 2021-2024.
7. Jafar TH. “Organ trafficking: global solutions for a global problem”. American Journal of Kidney Diseases6 (2009): 1145-1157.
8. Lv GC., et al. “Efficacy of combined therapy in patients with hepatitis B virus-related decompensated cirrhosis”. World Journal of Gastroenterology: WJG22 (2013): 3481.
9. Wijewantha HS. “Liver Disease in Sri Lanka”. Euroasian Journal of Hepato-Gastroenterology1 (2017): 78.
10. Tsochatzis EA., et al. “Liver cirrhosis”. The Lancet9930 (2014): 1749-1761.
11. Bennett JE., et al. “NCD Countdown 2030: worldwide trends in non-communicable disease mortality and progress towards Sustainable Development Goal target 3.4”. The Lancet 10152 (2018): 1072-1088.
12. Alberino F., et al. “Nutrition and survival in patients with liver cirrhosis”. Nutrition6 (2001): 445-450.
13. Middleton PF., et al. “Living donor liver transplantation—adult donor outcomes: a systematic review”. Liver Transplantation1 (2006): 24-30.
14. Thuluvath PJ., et al. “Liver transplantation in the United States, 1999–2008”. American Journal of Transplantation 10 (2010): 1003-1019.
15. Gibbs MA and Tayal VS. “Electrolyte disturbances. Rosen’s emergency medicine: Concepts and clinical practice”. (2006): 1724-1744.
16. John S and Thuluvath, PJ. “Hyponatremia in cirrhosis: pathophysiology and management”. World Journal of Gastroenterology: WJG11 (2015): 3197.
17. Musso G., et al. “Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis”. PLoS Medicine7 (2014): e1001680.
18. Kwak MS., et al. “Serum bilirubin levels are inversely associated with nonalcoholic fatty liver disease”. Clinical and Molecular Hepatology 4 (2012): 383.
19. Wolf DC. “Evaluation of the Size, Shape, and Consistency of the Liver”. In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths (1990).

Citation

Citation: Fahim Aslam and Shameemah Silmy. “Biochemical Liver Function Test in a Transplant Recipient: A Case Report" Acta Scientific Clinical Case Reports 1.7 (2020): 31-35.

Copyright

Copyright: © 2020 Fahim Aslam and Shameemah Silmy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.