Acta Scientific Cancer Biology (ASCB) (ISSN: 2582-4473)

Case Report Volume 4 Issue 11

Role of Fibroblast Activated PET-CT Scan to Evaluate Response to Eribulin in HER2 NEU Positive Metastatic Breast Cancer- A Case Report

Sweekruti Hegde, Ayesha Mahajan, Kruthikaa, Vinayak M, KG Kallur, Prasanth, BS Ajaikumar, Radheysham Naik and G Lohith*

Department of Radiation Oncology, Healthcare Global Hospital, Bangalore, India

*Corresponding Author: G Lohith, Department of Radiation Oncology, Healthcare Global Hospital, Bangalore, India.

Received: August 19, 2020; Published: October 20, 2020

×

Abstract

  We hereby report a case of a 44 year old female with invasive ductal carcinoma of left breast with metastasis to subcarinal and supraclavicular lymph nodes, right lung and left adrenal gland. She was diagnosed with fibroblast activated PET-CT and biopsy. Her PET-CT was done prior to chemotherapy and post chemotherapy and is further discussed in the report. She was operated (BCS) and received eribulin after a TCH regimen which showed regression of tumor in the fibroblast activated PET-CT. We further discuss how the fibroblasts in the cancer stroma is involved in the radionuclide based diagnosis of cancer. The presence of fibroblasts only in the tumor tissue that defines its accuracy in the cancer diagnosis. Eribulin is a microtubule inhibitor and reverses the epithelial mesenchymal transformation and hence is a effective drug in the treatment of different types of cancer. Eribulin has an effect on the cancer associated fibroblast that helps to use fibroblast activated PET CT as a method to measure the efficacy of Eribulin treatment in the breast cancer.

Keywords: Fibroblast; PET-CT Scan; Eribulin; HER2 NEU; Metastatic Breast Cancer

×

Citation

Citation: G Lohith., et al. “Role of Fibroblast Activated PET-CT Scan to Evaluate Response to Eribulin in HER2 NEU Positive Metastatic Breast Cancer- A Case Report". Acta Scientific Cancer Biology 4.11 (2020): 17-19.



Indexed In



News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is November 30, 2020.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US