Acta Scientific Biotechnology (ASBT)

Research Article Volume 1 Issue 3

Exploration of Biological Network Centralities with Cytoscape

Jagriti Singh, Farah Deeba, Gaurav Verma and Vinay Dwivedi*

Department of Biotechnology, Naraina Vidyapeeth Engineering and Management Institute, Panki, Kanpur, Uttar Pradesh, India

*Corresponding Author: Vinay Dwivedi, Department of Biotechnology, Naraina Vidyapeeth Engineering and Management Institute, Panki, Kanpur, Uttar Pradesh, India.

Received: February 22, 2020; Published: February 27, 2020

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Abstract

Background: System engendering is a significant and generally utilized calculation in the frameworks science, and bioinformatics, with applications in protein work forecast, sickness quality prioritization, and patient stratification designs and edges and hubs. In any case, up to the this point it has required noteworthy ability to run. Here we reach out to the famous system investigation program. Cytoscape to the perform organize proliferation as an incorporated capacity of the segment. Such combination incredibly expands the entrance to the system engendering by placing it in the hands of the researcher and connecting it to the numerous different kinds of the system investigation and the representation accessible through Cytoscape. We exhibit the force and utility of the calculation by the distinguishing changes giving protection from the Vemurafenib.

Keywords: Cytoscape; Interactive Network Visualization; Network Analysis

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References

  1. Batagelj V and Mrvar A. “Pajek-program for large network analysis”. Universityof Ljubljana (1999).
  2. Chatr-Aryamontri A., et al. “The BioGRID interaction database: 2013 update”. Nucleic Acids Research 41 (2013): D816-823.
  3. Csardi G and Nepusz T. “The I graph software package for complex network research”. International Journal of Complex Systems (2006).
  4. Doncheva NT., et al. “Analyzing and visualizing residue networks of protein structures”. Trends in Biochemical Sciences 36.4 (2011): 179-182.
  5. Köhler S., et al. “Walking the interactome for prioritization of candidate disease genes”. American Journal of Human Genetics 82.4 (2008): 949-958.
  6. Lee I., et al. “Prioritizing candidate disease genes by network-based boosting of genome-wide association data”. Genome Research 21.7 (2011): 1109-1121.
  7. Nabieva E., et al. “Whole-proteome prediction of protein function via graph-theoretic analysis of interaction maps”. Bioinformatics 21 (2005): 302-310.
  8. Qian Y., et al. “Identifying disease associated genes by network propagation”. BMC Systems Biology 8 (2014): S6.
  9. Shannon P., et al. “Cytoscape: a software environment for integrated models of biomolecular interaction networks”. Genome Research 13.11 (2003): 2498-504. 
  10. Smoot ME., et al. “Cytoscape 2.8: new features for data integration and network visualization”. Bioinformatics 27.3 (2011): 431-432.
  11. Suthram S., et al. “eQED: an efficient method for interpreting eQTL associations using protein networks”. Molecular Systems Biology 4 (2008): 162.
  12. Tu Z., et al. “An integrative approach for causal gene identification and gene regulatory pathway inference”. Bioinformatics 22 (2006): e489-496.
  13. Vanunu O., et al. “Associating Genes and Protein Complexes with Disease via Network Propagation”. PLOS Computational Biology 6 (2010): e1000641.
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Citation

Citation: Vinay Dwivedi., et al. “Exploration of Biological Network Centralities with Cytoscape".Acta Scientific Biotechnology 1.3 (2020): 16-20.




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